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Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety

BACKGROUND: A crucial gap in the development of microbicides for HIV prevention is the absence of models predictive of safety. Previous studies have demonstrated an increased susceptibility to genital herpes in mice following repeated applications of nonoxynol-9 (N-9). This study was designed to exp...

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Détails bibliographiques
Auteurs principaux: Wilson, Sarah S, Cheshenko, Natalia, Fakioglu, Esra, Mesquita, Pedro MM, Keller, Marla J, Herold, Betsy C
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879645/
https://ncbi.nlm.nih.gov/pubmed/20032541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1463
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