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Herpes Simplex Virus Downregulates Secretory Leukocyte Protease Inhibitor: a Novel Immune Evasion Mechanism

Secretory leukocyte protease inhibitor (SLPI), an anti-inflammatory mediator of mucosal immunity, inhibits human immunodeficiency virus (HIV) and herpes simplex virus (HSV) in cell culture. Epidemiological studies demonstrate that higher concentrations of SLPI in mucosal secretions are associated wi...

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Main Authors: Fakioglu, Esra, Wilson, Sarah S., Mesquita, Pedro M. M., Hazrati, Ehsan, Cheshenko, Natalia, Blaho, John A., Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546954/
https://ncbi.nlm.nih.gov/pubmed/18667508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00603-08
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