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Disruption of Tight Junctions by Cellulose Sulfate Facilitates HIV Infection: Model of Microbicide Safety

BACKGROUND: The lack of biomarkers that are predictive of safety is a critical gap in the development of microbicides. The present experiments were designed to evaluate the predictive value of in vitro models of microbicide safety. METHODS: Changes in the epithelial barrier were evaluated by measuri...

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Detalhes bibliográficos
Main Authors: Mesquita, Pedro M. M., Cheshenko, Natalia, Wilson, Sarah S., Mhatre, Mohak, Guzman, Esmeralda, Fakioglu, Esra, Keller, Marla J., Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877491/
https://ncbi.nlm.nih.gov/pubmed/19586414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600867
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