Candidate Topical Microbicides Bind Herpes Simplex Virus Glycoprotein B and Prevent Viral Entry and Cell-to-Cell Spread

Topical microbicides designed to prevent acquisition of sexually transmitted infections are urgently needed. Nonoxynol-9, the only commercially available spermicide, damages epithelium and may enhance human immunodeficiency virus transmission. The observation that herpes simplex virus (HSV) and huma...

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Main Authors: Cheshenko, Natalia, Keller, Marla J., MasCasullo, Veronica, Jarvis, Gary A., Cheng, Hui, John, Minnie, Li, Jin-Hua, Hogarty, Kathleen, Anderson, Robert A., Waller, Donald P., Zaneveld, Lourens J. D., Profy, Albert T., Klotman, Mary E., Herold, Betsy C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC415621/
https://ncbi.nlm.nih.gov/pubmed/15155195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2025-2036.2004
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