Candidate Topical Microbicides Bind Herpes Simplex Virus Glycoprotein B and Prevent Viral Entry and Cell-to-Cell Spread

Topical microbicides designed to prevent acquisition of sexually transmitted infections are urgently needed. Nonoxynol-9, the only commercially available spermicide, damages epithelium and may enhance human immunodeficiency virus transmission. The observation that herpes simplex virus (HSV) and huma...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Cheshenko, Natalia, Keller, Marla J., MasCasullo, Veronica, Jarvis, Gary A., Cheng, Hui, John, Minnie, Li, Jin-Hua, Hogarty, Kathleen, Anderson, Robert A., Waller, Donald P., Zaneveld, Lourens J. D., Profy, Albert T., Klotman, Mary E., Herold, Betsy C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2025-2036.2004
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