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Somatic hypermutation of immunoglobulin genes in human neonates
The antibody response in the young infant is limited in several ways; in particular, responses generally are of low affinity and restricted to IgM. This raises the question whether the affinity maturation process, consisting of somatic mutation of immunoglobulin genes coupled with selection of high-...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Science Inc
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904651/ https://ncbi.nlm.nih.gov/pubmed/9158112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3631264.x |
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