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Somatic mutation of immunoglobulin V(H)6 genes in human infants

Infants respond to antigen by making antibody that is generally of low affinity for antigen. Somatic hypermutation of immunoglobulin genes, and selection of cells expressing mutations with improved affinity for antigen, are the molecular and cellular processes underlying the maturation of antibody a...

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Bibliografske podrobnosti
Main Authors: Ridings, J, Dinan, L, Williams, R, Roberton, D, Zola, H
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905087/
https://ncbi.nlm.nih.gov/pubmed/9764600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00694.x
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