Patterns of Somatic Mutations in Immunoglobulin Variable Genes

The mechanism responsible for somatic mutation in the variable genes of antibodies is unknown and may differ from previously described mechanisms that produce mutation in DNA. We have analyzed 421 somatic mutations from the rearranged immunoglobulin variable genes of mice to determine (1) if the nuc...

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Hlavní autoři: Golding, G. Brian, Gearhart, Patricia J., Glickman, Barry W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
Témata:
Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203053/
https://ncbi.nlm.nih.gov/pubmed/3557109
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