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Somatic mutation of immunoglobulin V(H)6 genes in human infants
Infants respond to antigen by making antibody that is generally of low affinity for antigen. Somatic hypermutation of immunoglobulin genes, and selection of cells expressing mutations with improved affinity for antigen, are the molecular and cellular processes underlying the maturation of antibody a...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905087/ https://ncbi.nlm.nih.gov/pubmed/9764600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00694.x |
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