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Somatic hypermutation of immunoglobulin genes in human neonates
The antibody response in the young infant is limited in several ways; in particular, responses generally are of low affinity and restricted to IgM. This raises the question whether the affinity maturation process, consisting of somatic mutation of immunoglobulin genes coupled with selection of high-...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
1997
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904651/ https://ncbi.nlm.nih.gov/pubmed/9158112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3631264.x |
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