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Aging-Related Changes in the Nigrostriatal Dopamine System and the Response to MPTP in Nonhuman Primates: Diminished Compensatory Mechanisms as a Prelude to Parkinsonism

Aging is the most prominent risk factor for Parkinson’s disease. Yet, consensus of how advancing age may predispose the dopamine (DA) system to parkinsonism is lacking. Three age-ranges of female rhesus monkeys, 8–9, 15–17 and 21–31 years, received unilateral DA depletion with intracarotid 1-methyl-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Collier, Timothy J., Lipton, Jack, Daley, Brian F., Palfi, Stephane, Chu, Yaping, Sortwell, Caryl, Bakay, Roy A.E., Sladek, John R., Kordower, Jeffrey H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899875/
https://ncbi.nlm.nih.gov/pubmed/17254792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.11.013
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