Aging-Related Changes in the Nigrostriatal Dopamine System and the Response to MPTP in Nonhuman Primates: Diminished Compensatory Mechanisms as a Prelude to Parkinsonism

Aging is the most prominent risk factor for Parkinson’s disease. Yet, consensus of how advancing age may predispose the dopamine (DA) system to parkinsonism is lacking. Three age-ranges of female rhesus monkeys, 8–9, 15–17 and 21–31 years, received unilateral DA depletion with intracarotid 1-methyl-...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Collier, Timothy J., Lipton, Jack, Daley, Brian F., Palfi, Stephane, Chu, Yaping, Sortwell, Caryl, Bakay, Roy A.E., Sladek, John R., Kordower, Jeffrey H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899875/
https://ncbi.nlm.nih.gov/pubmed/17254792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.11.013
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים