Diminished Viability, Growth, and Behavioral Efficacy of Fetal Dopamine Neuron Grafts in Aging Rats with Long-Term Dopamine Depletion: An Argument for Neurotrophic Supplementation

We examined the behavioral and morphological correlates of the response to a single intrastriatal dispersed cell graft of fetal rat ventral mesencephalic tissue in male Fischer-344 rats of varying age (4, 17, and 24–26 months old) and history of mesostriatal dopamine (DA) depletion (1 or 14 months)....

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發表在:J Neurosci
Main Authors: Collier, Timothy J., Sortwell, Caryl E., Daley, Brian F.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782306/
https://ncbi.nlm.nih.gov/pubmed/10377363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-13-05563.1999
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