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Impact of Dendritic Spine Preservation in Medium Spiny Neurons on Dopamine Graft Efficacy and the Expression of Dyskinesias in Parkinsonian Rats

Dopamine deficiency associated with Parkinson’s disease (PD) results in numerous changes in striatal transmitter function and neuron morphology. Specifically, there is marked atrophy of dendrites and dendritic spines on striatal medium spiny neurons (MSN), primary targets of inputs from nigral dopam...

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Bibliografski detalji
Glavni autori: Soderstrom, Katherine E., O’Malley, Jennifer A., Levine, Nathan D., Sortwell, Caryl E., Collier, Timothy J., Steece-Collier, Kathy
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940228/
https://ncbi.nlm.nih.gov/pubmed/20105237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07077.x
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