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Striatal D1 medium spiny neuron activation induces dyskinesias in parkinsonian mice
BACKGROUND: Dyskinesias are a disabling motor complication that arises with prolonged L-dopa treatment. Studies using D1 receptor drugs and genetically modified mice suggest that medium spiny neurons expressing D1 receptors play a primary role in L-dopa-induced dyskinesias. However, the specific rol...
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| 出版年: | Mov Disord |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398928/ https://ncbi.nlm.nih.gov/pubmed/28256010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26955 |
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