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Cortical Regulation of Dopamine Depletion-Induced Dendritic Spine Loss in Striatal Medium Spiny Neurons

The proximate cause of Parkinson’s Disease is striatal dopamine depletion. Although no overt toxicity to striatal neurons has been reported in Parkinson’s Disease, one of the consequences of striatal dopamine loss is a decrease in the number of dendritic spines on striatal medium spiny neurons (MSNs...

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Main Authors: Neely, M. Diana, Schmidt, Dennis E., Deutch, Ariel Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094700/
https://ncbi.nlm.nih.gov/pubmed/17888581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.06.044
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