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Low Nigrostriatal Reserve for Motor Parkinsonism in Nonhuman Primates

OBJECTIVE: Nigrostriatal reserve refers to the threshold of neuronal injury to dopaminergic cell bodies and their terminal fields required to produce parkinsonian motor deficits. Inferential studies have estimated striatal dopamine reserve to be at least 70%. Knowledge of this threshold is critical...

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Autores principales: Tabbal, Samer D., Tian, LinLin, Karimi, Morvarid, Brown, Christopher A., Loftin, Susan K., Perlmutter, Joel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443325/
https://ncbi.nlm.nih.gov/pubmed/22836146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.07.008
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