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Validation of nigrostriatal PET measures: critical limits

OBJECTIVE: Molecular imaging and clinical endpoints are frequently discordant in Parkinson disease (PD) clinical trials raising questions about validity of these imaging measures to reflect disease severity. We compared striatal uptake for 3 PET tracers with in vitro measures of nigral cell counts a...

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Detalhes bibliográficos
Main Authors: Karimi, Morvarid, Tian, LinLin, Brown, Christopher A., Flores, Hubert P., Loftin, Susan K., Videen, Tom O., Moerlein, Stephen M., Perlmutter, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631302/
https://ncbi.nlm.nih.gov/pubmed/23423933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23798
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