Validation of nigrostriatal PET measures: critical limits

OBJECTIVE: Molecular imaging and clinical endpoints are frequently discordant in Parkinson disease (PD) clinical trials raising questions about validity of these imaging measures to reflect disease severity. We compared striatal uptake for 3 PET tracers with in vitro measures of nigral cell counts a...

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Autori principali: Karimi, Morvarid, Tian, LinLin, Brown, Christopher A., Flores, Hubert P., Loftin, Susan K., Videen, Tom O., Moerlein, Stephen M., Perlmutter, Joel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631302/
https://ncbi.nlm.nih.gov/pubmed/23423933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23798
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