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In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment

A single unilateral intracarotid infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) into non-human primates causes injury to the nigrostriatal pathway including nigral cell bodies, axons and striatal terminal fields. In this model, motor parkinsonism correlates well with the loss of nig...

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Bibliografische gegevens
Hoofdauteurs: Tian, LinLin, Karimi, Morvarid, Brown, Chris A, Loftin, Susan K, Perlmutter, Joel S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104119/
https://ncbi.nlm.nih.gov/pubmed/24845719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.05.009
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