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Knockdown of ACAT-1 Reduces Amyloidogenic Processing of APP
Previous studies have shown that acyl-coenzyme A:cholesterol acyl transferase (ACAT), an enzyme that controls cellular equilibrium between free cholesterol and cholesteryl esters, modulates proteolytic processing of APP in cell-based and animal models of Alzheimer’s disease. Here we report that ACAT...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1896096/ https://ncbi.nlm.nih.gov/pubmed/17412327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.03.056 |
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