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Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of senile dementia, characterized by neurofibrillary tangle and amyloid plaque in brain pathology. Major efforts in AD drug were devoted to the interference with the production and accumulation of amyloid-β peptide (Aβ), which plays a causal role in t...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Zhao, Jing, Liu, Xinyue, Xia, Weiming, Zhang, Yingkai, Wang, Chunyu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418514/
https://ncbi.nlm.nih.gov/pubmed/32848600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00137
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