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Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of senile dementia, characterized by neurofibrillary tangle and amyloid plaque in brain pathology. Major efforts in AD drug were devoted to the interference with the production and accumulation of amyloid-β peptide (Aβ), which plays a causal role in t...
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| Publié dans: | Front Mol Neurosci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418514/ https://ncbi.nlm.nih.gov/pubmed/32848600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00137 |
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