Size regulation of von Willebrand factor–mediated platelet thrombi by ADAMTS13 in flowing blood

The metalloproteinase ADAMTS13 regulates the size of released von Willebrand factor (VWF) multimers bound to endothelial cells, but it is unknown whether it can cleave plasma VWF during thrombogenesis. To address this issue, we perfused blood over immobilized VWF and used videomicroscopy to visualiz...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Donadelli, Roberta, Orje, Jennifer N., Capoferri, Cristina, Remuzzi, Giuseppe, Ruggeri, Zaverio M.
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
Hemostasis, Thrombosis, and Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895707/
https://ncbi.nlm.nih.gov/pubmed/16293606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2972
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky