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ADAMTS‐13 and bleeding phenotype in von Willebrand disease

BACKGROUND: The bleeding phenotype of von Willebrand disease (VWD) varies highly between patients and can only partly be explained by von Willebrand factor (VWF) parameters. By cleaving large VWF multimers into smaller, less active multimers, ADAMTS‐13 is an important regulator of VWF activity. Howe...

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Publicado en:Res Pract Thromb Haemost
Main Authors: Boender, Johan, Nederlof, Angelique, Meijer, Karina, Mauser‐Bunschoten, Evelien P., Cnossen, Marjon H., Fijnvandraat, Karin, van der Bom, Johanna G., de Meris, Joke, Laros‐van Gorkom, Britta A. P., van Galen, Karin P. M., Eikenboom, Jeroen, de Maat, Moniek P. M, Leebeek, Frank W. G.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695560/
https://ncbi.nlm.nih.gov/pubmed/33313472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12442
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