Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site

The function of von Willebrand factor (VWF) is regulated by proteolysis, which limits its multimeric size and ability to tether platelets. The importance of ADAMTS13 metalloprotease in VWF regulation is demonstrated by the association between severe deficiency of ADAMTS13 and thrombotic thrombocytop...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raife, Thomas J., Cao, Wenjing, Atkinson, Bonnie S., Bedell, Bruce, Montgomery, Robert R., Lentz, Steven R., Johnson, George F., Zheng, X. Long
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2009
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731642/
https://ncbi.nlm.nih.gov/pubmed/19541819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-195461
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak