von Willebrand factor–cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

Stroke is a leading cause of death and disability. The only therapy available is recombinant tissue plasminogen activator, but side effects limit its use. Platelets play a crucial role during stroke, and the inflammatory reaction promotes neurodegeneration. von Willebrand factor (VWF), an adhesion m...

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Detalhes bibliográficos
Main Authors: Zhao, Bing-Qiao, Chauhan, Anil K., Canault, Matthias, Patten, Ian S., Yang, Janie J., Dockal, Michael, Scheiflinger, Friedrich, Wagner, Denisa D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759655/
https://ncbi.nlm.nih.gov/pubmed/19687510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-213264
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