von Willebrand factor–mediated platelet adhesion is critical for deep vein thrombosis in mouse models

Deep vein thrombosis (DVT) and its complication, pulmonary embolism, are frequent causes of disability and mortality. Although blood flow disturbance is considered an important triggering factor, the mechanism of DVT initiation remains elusive. Here we show that 48-hour flow restriction in the infer...

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Main Authors: Brill, Alexander, Fuchs, Tobias A., Chauhan, Anil K., Yang, Janie J., De Meyer, Simon F., Köllnberger, Maria, Wakefield, Thomas W., Lämmle, Bernhard, Massberg, Steffen, Wagner, Denisa D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056477/
https://ncbi.nlm.nih.gov/pubmed/20959603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-287623
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