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von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins
von Willebrand factor (VWF) protects factor VIII (FVIII) from proteolysis and mediates the initial contact of platelets with the injured vessel wall, thus playing an important role in hemostasis and thrombosis. VWF is crucial for the formation of occlusive thrombi at arterial shear rates. However, w...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852205/ https://ncbi.nlm.nih.gov/pubmed/17119108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-028241 |
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