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Size regulation of von Willebrand factor–mediated platelet thrombi by ADAMTS13 in flowing blood
The metalloproteinase ADAMTS13 regulates the size of released von Willebrand factor (VWF) multimers bound to endothelial cells, but it is unknown whether it can cleave plasma VWF during thrombogenesis. To address this issue, we perfused blood over immobilized VWF and used videomicroscopy to visualiz...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
© 2006 by The American Society of Hematology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895707/ https://ncbi.nlm.nih.gov/pubmed/16293606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2972 |
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