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Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
von Willebrand factor (VWF) and the metalloprotease a disintegrin and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13) are present both within endothelial cells (ECs) and in peripheral blood. Calcium concentrations are lower in intracellular compartments (80-400 μM) compared with the e...
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| Publié dans: | Blood Adv |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728285/ https://ncbi.nlm.nih.gov/pubmed/29296853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009027 |
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