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Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13

von Willebrand factor (VWF) and the metalloprotease a disintegrin and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13) are present both within endothelial cells (ECs) and in peripheral blood. Calcium concentrations are lower in intracellular compartments (80-400 μM) compared with the e...

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Gogia, Shobhit, Kelkar, Anju, Zhang, Changjie, Dayananda, Kannayakanahalli M., Neelamegham, Sriram
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728285/
https://ncbi.nlm.nih.gov/pubmed/29296853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009027
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