Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13

Elevated plasma von Willebrand factor (VWF) and low ADAMTS13 activity have been reported in several inflammatory states, including sepsis and acute respiratory distress syndrome. One hallmark of inflammation is neutrophil activation and production of reactive oxygen species, including superoxide rad...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Junmei, Fu, Xiaoyun, Wang, Yi, Ling, Minhua, McMullen, Brad, Kulman, John, Chung, Dominic W., López, José A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810979/
https://ncbi.nlm.nih.gov/pubmed/19812385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-213967
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