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Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP

Infection or inflammation may precede and trigger formation of microvascular thrombosis in patients with acquired thrombotic thrombocytopenic purpura (TTP). However, the mechanism underlying this clinical observation is not fully understood. Here, we show that human neutrophil peptides (HNPs) releas...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Pillai, Vikram G., Bao, Jialing, Zander, Catherine B., McDaniel, Jenny K., Chetty, Palaniappan S., Seeholzer, Steven H., Bdeir, Khalil, Cines, Douglas B., Zheng, X. Long
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937355/
https://ncbi.nlm.nih.gov/pubmed/27207796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-688747
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