Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP

Infection or inflammation may precede and trigger formation of microvascular thrombosis in patients with acquired thrombotic thrombocytopenic purpura (TTP). However, the mechanism underlying this clinical observation is not fully understood. Here, we show that human neutrophil peptides (HNPs) releas...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Pillai, Vikram G., Bao, Jialing, Zander, Catherine B., McDaniel, Jenny K., Chetty, Palaniappan S., Seeholzer, Steven H., Bdeir, Khalil, Cines, Douglas B., Zheng, X. Long
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2016
Sujets:
Thrombosis and Hemostasis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937355/
https://ncbi.nlm.nih.gov/pubmed/27207796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-688747
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