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ADAMTS13 and von Willebrand factor interactions
PURPOSE OF REVIEW: ADAMTS13 is a zinc-containing metalloprotease that cleaves von Willebrand factor (VWF). Deficiency of plasma ADAMTS13 activity is accountable for a potentially fatal blood disorder thrombotic thrombocytopenic purpura (TTP). Understanding of ADAMTS13–VWF interaction is essential fo...
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| Pubblicato in: | Curr Opin Hematol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824554/ https://ncbi.nlm.nih.gov/pubmed/26186678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000169 |
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