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Factor VIII and Platelets Synergistically Accelerate Cleavage of von Willebrand Factor by ADAMTS13 under Fluid Shear Stress

Previous studies have demonstrated that factor VIII (FVIII) or platelets alone increase cleavage of von Willebrand factor (VWF) by ADAMTS13 under mechanically induced shear stresses. We show in this study that the combination of FVIII and platelets at the physiological concentrations is more effecti...

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Bibliografiset tiedot
Päätekijät: Skipwith, Christopher G., Cao, Wenjing, Zheng, X. Long
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937885/
https://ncbi.nlm.nih.gov/pubmed/20605782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.131227
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