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ADAMTS13 and von Willebrand factor interactions

PURPOSE OF REVIEW: ADAMTS13 is a zinc-containing metalloprotease that cleaves von Willebrand factor (VWF). Deficiency of plasma ADAMTS13 activity is accountable for a potentially fatal blood disorder thrombotic thrombocytopenic purpura (TTP). Understanding of ADAMTS13–VWF interaction is essential fo...

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Detalles Bibliográficos
Publicado en:Curr Opin Hematol
Main Authors: Zander, Catherine B., Cao, Wenjing, Zheng, X. Long
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824554/
https://ncbi.nlm.nih.gov/pubmed/26186678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000169
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