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Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors
Mast cells play a central role in inflammatory and immediate-type allergic reactions by secreting a variety of biologically active substances, including sphingosine-1 phosphate (S1P). Sphingosine kinase 1 (SphK1) and formation of S1P, which leads to transactivation of S1P receptors and their downstr...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society of Hematology
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1894993/ https://ncbi.nlm.nih.gov/pubmed/15741218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4686 |
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