The S1P(2) Receptor Negatively Regulates Platelet-Derived Growth Factor-Induced Motility and Proliferation

Sphingosine-1-phosphate (S1P), a bioactive sphingolipid metabolite, is the ligand for five specific G protein-coupled receptors, named S1P(1) to S1P(5). In this study, we found that cross-communication between platelet-derived growth factor receptor and S1P(2) serves as a negative damper of PDGF fun...

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Detalles Bibliográficos
Autores principales: Goparaju, Sravan K., Jolly, Puneet S., Watterson, Kenneth R., Bektas, Meryem, Alvarez, Sergio, Sarkar, Sukumar, Mel, Lin, Ishii, Isao, Chun, Jerold, Milstien, Sheldon, Spiegel, Sarah
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087716/
https://ncbi.nlm.nih.gov/pubmed/15870293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4237-4249.2005
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