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A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells

The bioactive phospholipids, lysophosphatidic acid (LPA) and phosphatidic acid (PA), regulate pivotal processes related to the pathogenesis of cancer. Here, we report characterization of a novel lipid kinase, designated acylglycerol kinase (AGK), that phosphorylates monoacylglycerol and diacylglycer...

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Detalhes bibliográficos
Main Authors: Bektas, Meryem, Payne, Shawn G., Liu, Hong, Goparaju, Sravan, Milstien, Sheldon, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171605/
https://ncbi.nlm.nih.gov/pubmed/15939762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407123
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