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Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget

The various sphingosine kinase (SphK) isoenzymes (isozymes) and isoforms, key players in normal cellular physiology, are strongly implicated in cancer and other diseases. Mutations in SphKs, that may justify abnormal physiological function, have not been recorded. Nonetheless, there is a large and g...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Hatoum, Diana, Haddadi, Nahal, Lin, Yiguang, Nassif, Najah T., McGowan, Eileen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482707/
https://ncbi.nlm.nih.gov/pubmed/28415564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16370
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