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PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the development and progression of cancers. Receptor tyrosine kina...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer
Hoofdauteurs: Haddadi, Nahal, Lin, Yiguang, Travis, Glena, Simpson, Ann M., McGowan, Eileen M., Nassif, Najah T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817727/
https://ncbi.nlm.nih.gov/pubmed/29455665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0803-3
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