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PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the development and progression of cancers. Receptor tyrosine kina...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Haddadi, Nahal, Lin, Yiguang, Travis, Glena, Simpson, Ann M., McGowan, Eileen M., Nassif, Najah T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817727/
https://ncbi.nlm.nih.gov/pubmed/29455665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0803-3
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