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“Dicing and Splicing” Sphingosine Kinase and Relevance to Cancer

Sphingosine kinase (SphK) is a lipid enzyme that maintains cellular lipid homeostasis. Two SphK isozymes, SphK1 and SphK2, are expressed from different chromosomes and several variant isoforms are expressed from each of the isozymes, allowing for the multi-faceted biological diversity of SphK activi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Haddadi, Nahal, Lin, Yiguang, Simpson, Ann M., Nassif, Najah T., McGowan, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618540/
https://ncbi.nlm.nih.gov/pubmed/28869494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091891
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