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Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget

The various sphingosine kinase (SphK) isoenzymes (isozymes) and isoforms, key players in normal cellular physiology, are strongly implicated in cancer and other diseases. Mutations in SphKs, that may justify abnormal physiological function, have not been recorded. Nonetheless, there is a large and g...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Hatoum, Diana, Haddadi, Nahal, Lin, Yiguang, Nassif, Najah T., McGowan, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482707/
https://ncbi.nlm.nih.gov/pubmed/28415564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16370
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