Targeting SphK1 as a New Strategy against Cancer

Sphingolipid metabolites have emerged as critical players in a number of fundamental biological processes. Among them, sphingosine-1-phosphate (S1P) promotes cell survival and proliferation, in contrast to ceramide and sphingosine, which induce cell growth arrest and apoptosis. These sphingolipids w...

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Библиографические подробности
Главные авторы: Shida, Dai, Takabe, Kazuaki, Kapitonov, Dmitri, Milstien, Sheldon, Spiegel, Sarah
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674575/
https://ncbi.nlm.nih.gov/pubmed/18691013
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