Increased T Cell Recruitment to the CNS after Amyloid β(1–42) Immunization in Alzheimer's Mice Overproducing Transforming Growth Factor-β1

Immunotherapy targeting the amyloid β (Aβ) peptide is a novel therapy under investigation for the treatment of Alzheimer's disease (AD). A clinical trial using Aβ(1–42) (AN1792) as the immunogen was halted as a result of development of meningoencephalitis in a small number of patients. The cyto...

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Hlavní autoři: Buckwalter, Marion S., Coleman, Bronwen S., Buttini, Manuel, Barbour, Robin, Schenk, Dale, Games, Dora, Seubert, Peter, Wyss-Coray, Tony
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892201/
https://ncbi.nlm.nih.gov/pubmed/17079673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2436-06.2006
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