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Increased T Cell Recruitment to the CNS after Amyloid β(1–42) Immunization in Alzheimer's Mice Overproducing Transforming Growth Factor-β1
Immunotherapy targeting the amyloid β (Aβ) peptide is a novel therapy under investigation for the treatment of Alzheimer's disease (AD). A clinical trial using Aβ(1–42) (AN1792) as the immunogen was halted as a result of development of meningoencephalitis in a small number of patients. The cyto...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892201/ https://ncbi.nlm.nih.gov/pubmed/17079673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2436-06.2006 |
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