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Theory of Lethal Mutagenesis for Viruses

Mutation is the basis of adaptation. Yet, most mutations are detrimental, and elevating mutation rates will impair a population's fitness in the short term. The latter realization has led to the concept of lethal mutagenesis for curing viral infections, and work with drugs such as ribavirin has...

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Bibliografische gegevens
Hoofdauteurs: Bull, J. J., Sanjuán, R., Wilke, C. O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865999/
https://ncbi.nlm.nih.gov/pubmed/17202214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01624-06
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