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Lethal Mutagenesis of Bacteria
Lethal mutagenesis, the killing of a microbial pathogen with a chemical mutagen, is a potential broad-spectrum antiviral treatment. It operates by raising the genomic mutation rate to the point that the deleterious load causes the population to decline. Its use has been limited to RNA viruses becaus...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567356/ https://ncbi.nlm.nih.gov/pubmed/18780744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091413 |
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