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Lethal Mutagenesis of Bacteria

Lethal mutagenesis, the killing of a microbial pathogen with a chemical mutagen, is a potential broad-spectrum antiviral treatment. It operates by raising the genomic mutation rate to the point that the deleterious load causes the population to decline. Its use has been limited to RNA viruses becaus...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bull, James J., Wilke, Claus O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567356/
https://ncbi.nlm.nih.gov/pubmed/18780744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091413
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