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Lethal mutagenesis in a structured environment

We analyze how lethal mutagenesis operates in a compartmentalized host. We assume that different compartments receive different amounts of mutagen and that virions can migrate among compartments. We address two main questions: 1. To what extent can refugia, i.e., compartments that receive little mut...

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Hlavní autoři: Steinmeyer, Shelby H., Wilke, Claus O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867491/
https://ncbi.nlm.nih.gov/pubmed/19627995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.07.014
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