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Theory of Lethal Mutagenesis for Viruses
Mutation is the basis of adaptation. Yet, most mutations are detrimental, and elevating mutation rates will impair a population's fitness in the short term. The latter realization has led to the concept of lethal mutagenesis for curing viral infections, and work with drugs such as ribavirin has...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865999/ https://ncbi.nlm.nih.gov/pubmed/17202214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01624-06 |
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