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Lethal Mutagenesis of Foot-and-Mouth Disease Virus Involves Shifts in Sequence Space
Lethal mutagenesis or virus transition into error catastrophe is an antiviral strategy that aims at extinguishing a virus by increasing the viral mutation rates during replication. The molecular basis of lethal mutagenesis is largely unknown. Previous studies showed that a critical substitution in t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209394/ https://ncbi.nlm.nih.gov/pubmed/21917974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00716-11 |
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